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Gynovite® Plus is a complete nutritional supplement formulated for postmenopausal complaints. This
supplement emphasized magnesium over calcium. Based on a review of the published literature, the
information available does not support an important role of calcium in osteoporosis.

In laboratory animals studied, calcium deficiency causes osteo-malacia (soft bone), not osteoporosis
(porous bone). However magnesium deficiency resulted in osteoporosis(1). Countries with the highest
consumption of calcium had the highest incidence of hip fracture. The lowest hip fracture rates in post
menopausal women were observed in countries with daily calcium intake as low as 400-500 mg(1). Several
other nutrients play an important role in bone integrity and these nutrients are in Gynovite®.

An increase in bone density was observed in 19 post-menopausal women following supplementation with
Gynovite®(1). Compared to a 0.7% increase in 7 women not on Gynovite®, a increase of 11% was observed
in the 19 women followed for the same period of time less than one year. Repeated bone density measure
following 2 years on Gynovite® showed a further increase in bone density (1). Fifteen of the 19 women were
below fracture threshold at the beginning of the study. Within one year only 7 of them still had values below
that threshold (2).

Gynovite Plus contains the following ingredients:

    Vitamin A  50,000 IU (as retinyl palmitate)
    Vitamin C  180 MG
    Vitamin D  400 IU (as cholecalciferol)
    Vitamin E   400 IU (as d-alpha tocopheryl succinate)
    Thiamin   10 MG (as thiamine mononitrite)
    Riboflavin 10 MG
    Niacin 20 MG (as niacinamide)
    Vitamin B6 20 MG (as pyridoxine)
    Folic Acid  400 MCG
    Vitamin B12  125 MG (as hydroxocobalamin)
    Biotin   125 MG
    Pantothenic Acid 10 MG (as Ca Pantothenate)
    Calcium   500 MG (as Calcium Citrate)
    Iron  18 MG (as amino acid chelate)
    Iodine  150 MCG (as hydolyzed protein complex)
    Magnesium 600 MG (as magnesium oxide)
    Zinc 15mg (as amino acid chelate)
    Selenium 200 MCG (as hydrolyzed protein complex)
    Copper  2 MG (as amino acid chelate)
    Manganese  10 mg (as amino acid chelate)
    Chromium  200 MCG (as hydrolyzed protein complex)
    P-Amino Benzoic Acid (PABA)  25 MG
    Betaine HCI  100 MG
    Pancreatin 4X 93 MG
    Inositol 50 MG
    Hesperidin  35 MG
    Rutin  25 MG
    Boron  3 MG (as hydrolyzed protein complex)

Other ingredients include Micosolle, (a silica-based oxoipient containing a non-ionic
surfactant, cellulose and modified cellulose, silica, stearic acid, pharmaceutical glaze,
magnesium stearate, natural flavor, and cranberry powder as natural source of color.


For best results, Gynovite® should be used as part of a total dietary program.
1] Abraham, G.E., The Importance of Magnesium in the Management of Primary Postmenopausal
Osteoporosis, J. Nut. Med., 2:165-178, 1991.
2] Abraham, G.E., Grewal, H., A Total Dietary Program Emphasizing Magnesium Instead of Calcium: Effect on
the Mineral Density of Calcaneous Bone in Postmenopausal Women on Hormonal Therapy, J. Rep. Med., 35:
503, 1990.

SUGGESTED USE:
Six tablets daily with meals as a dietary supplement, or as directed by a physician.
WARNING:
Do not use if outer seal is broken.
If taking any prescription drug, consult physician before use.
Do not use for pernicious anemia, or if you have hemochromatosis or hemosiderosis.

Read brochure inside bottle before use.


Accidental over dose of iron-containing products is a leading causes of fatal poisoning in children under 6.
Keep this product out of the reach of children. In case of accidental overdose, call a doctor or poison control
center immediately.  
Store in a cool, dry place.
Manufactured for:
Optimox Corporation
Torrance, CA 90510-3378
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